CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 30 enrolled
Drug / intervention
Metformin +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02986659
NCT02986659Phase 4Completed

Genomic Outcomes of Metformin

Wake Forest University Health Sciences·interventional·Posted Dec 8, 2016·Updated Nov 18, 2023

In Brief

A Phase 4 clinical trial evaluating Metformin and Placebo for Coronary Artery Disease and 3 related conditions. Completed, enrolled 30 participants across 1 site.

Detailed Summary

Medical scientists have found that people with diabetes who take the drug Metformin have less age-related disease than those taking other treatments and researchers believe it may prevent numerous diseases and conditions that effect older people. In addition, metformin extends lifespan in some animal models of human disease. The purpose of this study is to see if taking Metformin causes changes in blood cells consistent with improved health and longevity in people who do not have diabetes. In this study Metformin will be compared to placebo. A placebo is a substance, like a sugar pill, that is not thought to have any effect on a participants disease or condition. In this study participants will either receive the active study medication, Metformin or placebo which is not active. Placebos are used in research studies to see if the drug being studied really does have an effect.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 4CompletedFinished
2017201820192020202120222023202420252026
First PostedDec 8, 2016
Enrollment StartAug 3, 2016
Primary CompletionNov 15, 2018
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 9.6 years ago

Interventions

Metformindrug

Placebodrug