CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 60 enrolled
Drug / intervention
Remifentanil +5 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02988050
NCT02988050N/ACompleted
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Propofol-dexmedetomidine Versus Propofol-remifentanil Conscious Sedation for Awake Craniotomy During Epilepsy Surgery

Menoufia University·interventional·Posted Dec 9, 2016·Updated Oct 9, 2020

In Brief

A clinical study evaluating Remifentanil, Dexmedetomidine, and 4 other interventions for Epilepsy. Completed, enrolled 60 participants.

Detailed Summary

Sixty patients were randomly allocated into two groups, group PD and group PR, thirty patients in each group. Patients in PD group received propofol and dexmedetomidine intravenous infusion and patients in PR group received propofol and remifentanil intravenous infusion. Sedation score and patients' satisfaction, surgeon satisfaction, heart rate, mean arterial blood pressure, oxygen saturation, and side effects such as respiratory depression, nausea, vomiting, airway obstruction, and oxygen desaturation were recorded.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsEpilepsy
Countries--
Collaborators--

Timeline

N/ACompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedDec 9, 2016
Enrollment StartAug 1, 2013
Primary CompletionFeb 1, 2016
Study CompletionApr 1, 2016
TodayJul 2, 2026
Enrollment to primary: 2.5 yearsPosted 9.6 years ago

Interventions

Remifentanildrug

Remifentanil used for conscious sedation.

Dexmedetomidinedrug

Dexmedetomidine used for conscious sedation.

Propofoldrug

Used for conscious sedation.

Bupivacainedrug

Local anaesthetics

Lidocainedrug

Local anaesthetic

Epinephrinedrug

With local anaesthetic for skin infiltration.