CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 32 enrolled
Drug / intervention
Ventilator protocol +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02989246
NCT02989246N/ACompleted

Effort of Breathing Guided Ventilator Management for Children Using Pressure Rate Product: a Pilot Study

Children's Hospital Los Angeles·interventional·Posted Dec 12, 2016·Updated Oct 30, 2024

In Brief

A clinical study evaluating Ventilator protocol and Esophageal Catheter for Ventilators, Mechanical and Work of Breathing. Completed, enrolled 32 participants across 1 site.

Detailed Summary

This pilot study tests the feasibility of using a computerized ventilator management protocol seeking to encourage lung protective ventilation during the acute phase of ventilation, and esophageal manometry based titration of ventilator settings during the weaning phase of ventilation, for children with acute respiratory failure. The investigators hypothesize that such an approach will reduce time on mechanical ventilation, largely by preserving diaphragm muscle function.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
201520162017201820192020202120222023202420252026
First PostedDec 12, 2016
Enrollment StartFeb 1, 2015
Primary CompletionOct 18, 2017
Study CompletionDec 1, 2018
TodayJul 2, 2026
Enrollment to primary: 2.7 yearsPosted 9.6 years ago

Interventions

Ventilator protocolother

Open loop ventilator management by a computer based protocol

Esophageal Catheterdevice

Esophageal manometry measurements of patient effort of breathing will be used to guide the protocol recommendations