At a glance
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Persistent Symptoms and Early Incomplete Recovery After Acute Stress-induced Cardiomyopathy: Is There Ongoing Heart Distress? The HEROIC Study
In Brief
An observational study evaluating Assessment of exercise capacity and cardiac energetics for Tako-tsubo Cardiomyopathy. Completed, enrolled 42 participants across 1 site.
Detailed Summary
Acute stress induced (Tako-tsubo) cardiomyopathy (TTC) or broken heart syndrome, a condition typically occurring after acute stress has a death rate similar to heart attacks and is frequently associated with long-term symptoms (fatigue and exercise limitation). There are no effective therapies. The investigators have recently showed that there is a profound shortage of energy in the hearts of Tako Tsubo Cardiomyopathy patients in the days after acute presentation with only partial recovery by four months. The investigators would now like to establish whether this recovers after at least one year, or persists, and also to investigate the mechanisms responsible for exercise limitation after recovery from the acute phase.
Study Details
Timeline
Interventions
Cardiopulmonary exercise testing and Magnetic Resonance Spectroscopy