At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 68 enrolled
Drug / intervention
Raltitrexed +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Multicenter, Phase II Study of Preoperative Chemoradiotherapy With Raltitrexed for Intermediate or Locally Advanced Rectal Cancer in the Fit Elderly
In Brief
A Phase 2 clinical trial evaluating Preoperative radiation, Raltitrexed, and 1 other intervention for Rectal Neoplasms Malignant. Completed, enrolled 68 participants across 1 site.
Detailed Summary
The aim of this multicenter phase II study is to evaluate the response rate, local control, disease-free survival and treatment-related toxicity of preoperative chemoradiation for intermediate or locally advanced rectal cancer in the fit elderly.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsRectal Neoplasms Malignant
CountriesChina
Collaborators--
Timeline
Phase 2CompletedFinished
2017201820192020202120222023202420252026
Enrollment StartSep 2016
First PostedDec 2016
Primary CompletionMay 2021
Study CompletionAug 2021
TodayJul 2026
First PostedDec 14, 2016
Enrollment StartSep 1, 2016
Primary CompletionMay 1, 2021
Study CompletionAug 1, 2021
TodayJul 2, 2026
Enrollment to primary: 4.7 yearsPosted 9.5 years ago
Interventions
Preoperative radiationradiation
Radiation treatment before surgery
Raltitrexeddrug
concurrent chemotherapy
Pelvic surgeryprocedure