CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 535 enrolled
Drug / intervention
Estradiol +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02995694
NCT02995694Phase 3Completed

Clinical Endpoint Therapeutic Equivalence Multi-Site Study Comparing Estradiol Vaginal Cream (0.01%; Alvogen Pine Brook LLC.) to Estrace® Cream (0.01%; Warner Chilcott) in Postmenopausal Females With Atrophic Vaginitis

Alvogen Pine Brook LLC·interventional·Posted Dec 16, 2016·Updated Dec 1, 2021

In Brief

A Phase 3 clinical trial evaluating Estradiol, Placebos, and 1 other intervention for Atrophic Vaginitis. Completed, enrolled 535 participants.

Detailed Summary

The purpose of this study is to determine the therapeutic equivalence of Alvogen's estradiol vaginal cream to Estrace® cream and superiority of both products to placebo. The protocol describes a randomized, double-blind, multi-dose, placebo-controlled, parallel study of a 7 day treatment.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
Countries--
Collaborators--

Timeline

Phase 3CompletedFinished
20162017201820192020202120222023202420252026
First PostedDec 16, 2016
Enrollment StartMar 1, 2016
Primary CompletionDec 1, 2016
TodayJul 2, 2026
Enrollment to primary: 9 monthsPosted 9.5 years ago

Interventions

Estradioldrug

Estradiol Vaginal Cream

Placebosdrug

Placebo with no active pharmaceutical ingredients. Topical vaginal cream

Referencedrug

Estrace Vaginal Cream