CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 45 enrolled
Drug / intervention
Bupropion +4 moredrug
Likely dose
Bupropion 150 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02995915
NCT02995915Phase 4Completed

Mobile Contingency Management for Concurrent Abstinence From Alcohol and Smoking

Duke University·interventional·Posted Dec 19, 2016·Updated Apr 28, 2021

In Brief

A Phase 4 clinical trial evaluating Nicotine Replacement Therapy, Bupropion, and 3 other interventions for Smoking Cessation and Alcohol Drinking. Completed, enrolled 45 participants across 1 site.

Detailed Summary

Alcohol misuse and smoking constitute two of the three leading preventable causes of death in the United States. The purpose of this research study is to develop an intervention designed to help people stop drinking alcohol and stop smoking at the same time.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
2017201820192020202120222023202420252026
First PostedDec 19, 2016
Enrollment StartNov 1, 2016
Primary CompletionMar 2, 2020
TodayJul 2, 2026
Enrollment to primary: 3.3 yearsPosted 9.5 years ago

Interventions

Nicotine Replacement Therapyother

Participants will be prescribed NRT patch and one nicotine rescue method (e.g., nicotine gum, lozenge, inhaler) for use during the post-quit phase of the study. Participants will be given the choice between nicotine gum or nicotine lozenge, and will be instructed to use the rescue method as needed to reduce cigarette cravings

Bupropiondrug

All participants who are medically eligible will be prescribed bupropion, which they will start two weeks prior to their quit day. Dosage will be 150 mg/daily for days 1-7 and 300 mg/daily (administered in two daily doses) until the 6-month follow-up.

Cognitive Behavioral Treatmentbehavioral

Participants will receive 4 60-minute sessions of CBT telephone counseling for alcohol and smoking cessation.

Mobile Contingency Managementbehavioral

Participants will be asked to provide video recordings of themselves taking carbon monoxide readings in order to confirm smoking abstinence, and breathalyzer to confirm abstinence from alcohol. Participants are asked to upload these videos to the study's secured server, and are provided monetary reward for videos that suggest smoking abstinence and alcohol abstinence.

Mobile Monitoringbehavioral

Participants will be asked to provide video recordings of themselves taking carbon monoxide readings and breathalyzer. Participants are asked to upload these videos to the study's secured server, and are provided monetary reward for providing the video recordings, regardless of abstinence.