CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 30 enrolled
Drug / intervention
Intralesional Triamcinolone Acetonide +1 moredrug
Likely dose
Intralesional triamcinolone acetonide (dose not specified); fractional CO2 laser using standard protocolAI-extracted
Key inclusion· 4
  • Age older than 17 at screening
  • Healthy per investigator assessment
  • At least two keloids of comparable size and texture on same general anatomic location (trunk or back)
  • Willing to comply with protocol visits and 4-week washout period
Key exclusion· 6
  • Pregnancy or breastfeeding, or planning pregnancy during study
  • History of coagulopathy
  • Current anticoagulant or antiplatelet therapy
  • Known allergy or sensitivity to local anesthetics (EMLA, tetracaine 7%/lidocaine 23%) or local antiseptics planned for laser

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02996097
NCT02996097N/ACompleted

Fractional Laser Assisted Steroid Therapy vs Intralesional Steroids in the Treatment of Keloids

Johns Hopkins University·interventional·Posted Dec 19, 2016·Updated Dec 17, 2020

In Brief

A clinical study evaluating The Lutronic electronic carbon dioxide (eCO2) Plus laser system and Intralesional Triamcinolone Acetonide for Keloid. Completed, enrolled 30 participants across 1 site.

Detailed Summary

The purpose of this study is to compare the effects of fractional carbon dioxide (CO2) laser therapy immediately followed by intralesional steroid therapy against intralesional steroid therapy alone for the treatment of keloids.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsKeloid
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedDec 19, 2016
Enrollment StartApr 1, 2016
Primary CompletionJun 15, 2018
TodayJul 2, 2026
Enrollment to primary: 2.2 yearsPosted 9.5 years ago

Interventions

The Lutronic electronic carbon dioxide (eCO2) Plus laser systemdevice

CO2 ablative laser plus intralesional triamcinolone acetonide A topical EMLA cream or tetracaine 7%/lidocaine 23% will be applied to the both treatment sites and after sufficient anesthesia is attained, one keloid will be treated with the fractional CO2 laser using standard protocol as practiced in our clinics followed by intralesional triamcinolone acetonide. One lesion would be treated with fractional CO2 ablative laser followed with intralesional triamcinolone acetonide at 4 weeks intervals

Intralesional Triamcinolone Acetonidedrug