CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 139 enrolled
Drug / intervention
Stepped care for depressionbehavioral
Likely dose
Cognitive behavior therapy (CBT), plus optional antidepressant medications per treating physicianAI-extracted
Key inclusion· 3
  • Stable, clinically-documented New York Heart Association (NYHA) Class I-III heart failure
  • Current major depressive episode
  • Beck Depression Inventory (BDI-II) score 14 or greater
Key exclusion· 8
  • Dementia or other significant cognitive or communication deficits
  • Terminal illness other than heart failure
  • Age less than 25 years
  • Current clinically significant substance abuse, bipolar disorder, schizophrenia, or other psychotic disorder

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02997865
NCT02997865N/ACompleted

Stepped Care for Depression in Heart Failure

Washington University School of Medicine·interventional·Posted Dec 20, 2016·Updated Feb 10, 2023

In Brief

A clinical study evaluating Stepped care for depression for Heart Failure and Depressive Disorder, Major. Completed, enrolled 139 participants across 1 site.

Detailed Summary

This study evaluates stepped care for depression in patients with heart failure (HF). The stepped care intervention consists of individualized cognitive behavior therapy (CBT). Half of the participants will receive stepped care and half will receive usual care for depression; all participants will receive heart failure self-care education and support. The primary aims are to determine whether stepped care is superior to usual care for depression, and whether treating depression improves heart failure self-care outcomes.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
2017201820192020202120222023202420252026
First PostedDec 20, 2016
Enrollment StartFeb 17, 2017
Primary CompletionJul 31, 2021
Study CompletionDec 31, 2021
TodayJul 2, 2026
Enrollment to primary: 4.5 yearsPosted 9.5 years ago

Interventions

Stepped care for depressionbehavioral

Cognitive behavior therapy (CBT), plus referral to the participant's own physician to discuss antidepressant medications if indicated.