At a glance

ClinicalIndex Comparison Record

N/ACompleted· 163 enrolled

Drug / intervention

LFR followed by HFL +1 moredevice

Likely dose

Not stated in record

Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02998580

NCT02998580N/ACompleted

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Conventional Bilateral rTMS vs. Bilateral Theta Burst Stimulation for Late-Life Depression

Centre for Addiction and Mental Health·interventional·Posted Dec 20, 2016·Updated Feb 20, 2024

In Brief

A clinical study evaluating LFR followed by HFL and cTBS followed by iTBS for Major Depression. Completed, enrolled 163 participants across 1 site.

Detailed Summary

This trial will compare conventional sequential bilateral rTMS to a bilateral theta burst stimulation protocol. The right and left dorsolateral prefrontal cortices will be the site of stimulation in both treatment conditions. The site of stimulation will be targeted using MRI co-registration. The study seeks to determine if the bilateral theta burst protocol has similar effectiveness to the conventional bilateral rTMS protocol in treating major depression.

Study Details

Study Typeinterventional

Allocation--

Masking--

Primary Purpose--

ConditionsMajor Depression

CountriesCanada

CollaboratorsUniversity Health Network, Toronto

Timeline

N/ACompletedFinished

2017201820192020202120222023202420252026

Enrollment StartDec 2016

First PostedDec 2016

Primary CompletionApr 2020

TodayJul 2026

First PostedDec 20, 2016

Enrollment StartDec 1, 2016

Primary CompletionApr 24, 2020

TodayJul 2, 2026

Enrollment to primary: 3.4 yearsPosted 9.5 years ago

Interventions

LFR followed by HFLdevice

Magventure Cool B70 Coil with RX100 Stimulator

cTBS followed by iTBSdevice

Magventure Cool B70 Coil with RX100 Stimulator