CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 753 enrolled
Drug / intervention
SHP640 +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03004924
NCT03004924Phase 3Completed

A Phase 3, Multi-center, Randomized, Double-Masked Study to Evaluate the Clinical Efficacy and Safety of SHP640 (PVP-Iodine 0.6% and Dexamethasone 0.1%) Ophthalmic Suspension Compared to Placebo in the Treatment of Bacterial Conjunctivitis

Shire·interventional·Posted Dec 29, 2016·Updated Jun 9, 2021

In Brief

A Phase 3 clinical trial evaluating SHP640, PVP-I 0.6%, and 1 other intervention for Bacterial Conjunctivitis. Completed, enrolled 753 participants across 163 sites in 13 countries.

Detailed Summary

The purpose of this study is to determine if an investigational treatment is effective compared with placebo and PVP-Iodine in the treatment of adults and children with bacterial conjunctivitis.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, Austria, Canada, Estonia, France, Hungary, Israel, Italy, Poland, Puerto Rico, South Africa, Spain, United States
Collaborators--

Timeline

Phase 3CompletedFinished
2017201820192020202120222023202420252026
First PostedDec 29, 2016
Enrollment StartMar 29, 2017
Primary CompletionOct 1, 2018
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 9.5 years ago

Interventions

SHP640drug

Instill 1 drop of SHP640 (povidone-iodine \[PVPI\] 0.6% and Dexamethasone 0.1%) ophthalmic suspension in each eye QID (with a minimum of 2 hours between doses) for 7 days.

PVP-I 0.6%drug

Instill 1 drop of PVP-I 0.6% ophthalmic solution in each eye 4 times QID (with a minimum of 2 hours between doses) for 7 days.

Placebodrug

Instill 1 drop of placebo ophthalmic solution in each eye 4 times QID (with a minimum of 2 hours between doses) for 7 days.