At a glance

ClinicalIndex Comparison Record

Phase 2Completed· 62 enrolled

Drug / intervention

Morphine +1 moredrug

Likely dose

Morphine 1 mgfrom record

Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03005548

NCT03005548Phase 2Completed

Compare CT.gov

Cortical Modulation of Acute Post-thoracotomy Pain With Transcranial Direct Current Stimulation

Military Medical Academy, Belgrade, Serbia·interventional·Posted Dec 29, 2016·Updated Mar 29, 2018

In Brief

A Phase 2 clinical trial evaluating Transcranial direct current stimulation and Morphine for Pain, Postoperative. Completed, enrolled 62 participants across 1 site.

Detailed Summary

The primary objective of this single center, prospective, randomized, double blind clinical trial is to evaluate the effectiveness of anodal transcranial direct current stimulation (tDCS) combined with patient controlled analgesia (PCA) morphine, on intravenous morphine use for postoperative analgesia after thoracotomy. The intervention group will receive treatment with anodal tDCS, whereas the control group will receive sham stimulation.

Study Details

Study Typeinterventional

Allocation--

Masking--

Primary Purpose--

ConditionsPain, Postoperative

CountriesSerbia

Collaborators--

Timeline

Phase 2CompletedFinished

2017201820192020202120222023202420252026

Enrollment StartJun 2016

First PostedDec 2016

Primary CompletionDec 2017

Study CompletionJan 2018

TodayJul 2026

First PostedDec 29, 2016

Enrollment StartJun 1, 2016

Primary CompletionDec 1, 2017

Study CompletionJan 1, 2018

TodayJul 2, 2026

Enrollment to primary: 1.5 yearsPosted 9.5 years ago

Interventions

Transcranial direct current stimulationdevice

Transcranial direct current stimulation. All eligible patients will be treated with patient-controlled IV morphine analgesia by PCA (PCA pump (CADD-Legacy PCA Pump, Deltec, Inc.) IV morphine bolus 1 mg, lockout time 10 mins.). Device: wireless tDCS (StarStim, NeuroElectrics) non-invasive brain stimulation with a pair of electrodes with saline-soaked pads for delivery of direct current at intensity 2 mA for 20 mins.

Morphinedrug

In Sham comparator group All eligible patients will be treated with patient-controlled IV morphine analgesia (PCA) (PCA pump (CADD-Legacy PCA Pump (Deltec, Inc.) morphine IV bolus 1 mg, lockout time 10 mins). Device: wireless tDCS (StarStim, NeuroElectrics) non-invasive brain stimulation with a pair of electrodes with saline-soaked pads for delivery of direct current at intensity 2 mA for 30s at the beginning.