CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 75 enrolled
Drug / intervention
Morphine intrathecal +2 moredrug
Likely dose
Morphine intrathecal 0.3 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03007121
NCT03007121Phase 4Completed
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Comparison of Intrathecal Morphine, Epidural Bupivacaine With Sufentanil and Systemic Patient Controlled Analgesia With Morphine for Analgesia After Colorectal Surgery: Prospective Randomised Study.

Charles University, Czech Republic·interventional·Posted Jan 2, 2017·Updated Jan 31, 2019

In Brief

A Phase 4 clinical trial evaluating Morphine intrathecal, Bupivacaine + Sufentanil epidural, and 1 other intervention for Analgesia, Patient-Controlled and 5 related conditions. Completed, enrolled 75 participants across 1 site.

Detailed Summary

The purpose of this study is to determine which postoperative analgesia is optimal after colorectal surgery. The investigators will compare intrathecal morphine, continuous epidural analgesia and standard systemic analgesia. All patients will have the possibility to administer themselves intravenous morphine as needed.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAnalgesia, Patient-Controlled, Epidural Analgesia, Anesthesia; Spinal, Morphine, Surgery, Colorectal, Intravenous Drug Delivery Systems
CountriesCzechia
Collaborators--

Timeline

Phase 4CompletedFinished
2017201820192020202120222023202420252026
First PostedJan 2, 2017
Enrollment StartApr 10, 2017
Primary CompletionDec 14, 2018
Study CompletionDec 17, 2018
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 9.5 years ago

Interventions

Morphine intrathecaldrug

Administration of intrathecal injection of 0.3 mg preservative-free morphine in 3 ml NS

Bupivacaine + Sufentanil epiduraldrug

Continuous epidural infusion of a mixture containing in 1 ml bupivacaine 0,125% and sufentanil 0,4 mcg at 8 ml/h.

Morphine intravenousdrug

Patiernt-controlled i.v. analgesia with morphine