CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 250 enrolled
Drug / intervention
Eziclen®/Izinova® +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03008460
NCT03008460Phase 3Completed

Efficacy, Safety and Tolerability of a Bowel Cleansing Preparation (Eziclen/Izinova®) in Paediatric Subjects Undergoing Colonoscopy: a Phase III, Multicentre, Randomised, Comparative Study Versus Klean-Prep® (PEG-Electrolytes), Administered on the Day Before Colonoscopy, Investigator-blinded, Non-inferiority in Adolescents of 12 to 17 Years of Age (Inclusive) >40 kg

Ipsen·interventional·Posted Jan 2, 2017·Updated Mar 2, 2021

In Brief

A Phase 3 clinical trial evaluating Eziclen®/Izinova® and Klean-Prep® for Digestive System Disease. Completed, enrolled 250 participants across 24 sites in 6 countries.

Detailed Summary

The purpose of the protocol is to demonstrate that Eziclen®/Izinova®, an osmotic sulphate-based laxative preparation given on the day before colonoscopy has non-inferior efficacy to Klean-Prep® (polyethylene glycol (PEG)-electrolytes) on colon cleansing in adolescents aged 12 to 17 years (inclusive) with a body weight \>40 kg, scheduled to undergo a colonoscopy for a routinely accepted diagnostic indication.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCzechia, France, Germany, Italy, Netherlands, Poland
Collaborators--

Timeline

Phase 3CompletedFinished
2017201820192020202120222023202420252026
First PostedJan 2, 2017
Enrollment StartOct 15, 2017
Primary CompletionFeb 24, 2020
Study CompletionJun 29, 2020
TodayJul 2, 2026
Enrollment to primary: 2.4 yearsPosted 9.5 years ago

Interventions

Eziclen®/Izinova®drug

Oral solution taken the evening before the colonoscopy

Klean-Prep®drug

Oral solution taken the evening before the colonoscopy