At a glance
ClinicalIndex Comparison Record- ✓Delivery at ≥24 weeks gestational age
- ✓Diagnosis of hypertensive disorder of pregnancy: gestational hypertension, preeclampsia (with or without severe features), HELLP syndrome, or eclampsia
- ✓Receiving care through Women's Perinatal Group (MFM) or Obstetric Clinic resident services
- ✕Chronic hypertension or elevated blood pressures before 20 weeks gestational age
- ✕Severe hypertension (≥160 mmHg systolic or ≥105 mmHg diastolic) prior to randomization
- ✕Renal dysfunction (serum creatinine >1.3 mg/dL)
- ✕Low platelet count (<50,000)
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Randomized Controlled Trial on the Effects of NSAIDs on Postpartum Blood Pressure in Patients Hypertensive Disorders of Pregnancy
In Brief
A clinical study evaluating Acetaminophen and Ibuprofen for Hypertension, Pregnancy-Induced. Completed, enrolled 202 participants across 1 site.
Detailed Summary
This study aims to evaluate whether NSAIDs (Non-steroidal antiinflammatory drugs) administered during the postpartum period influence blood pressure in women with hypertensive disorders of pregnancy. The study design is a prospective double blinded randomized control trial with participants randomized to receive postpartum analgesic regimens with and without NSAIDs.
Study Details
Timeline
Interventions
Participants will receive acetaminophen for postpartum mild pain relief
Participants will receive ibuprofen for postpartum mild pain relief