At a glance
ClinicalIndex Comparison RecordN/ACompleted· 100 enrolled
Drug / intervention
Low pressure pneumoperitoneum +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Characterization of Changes in Peritoneal Cells Gene Expression After Standard Versus Low Pressure Laparoscopic Cholecystectomy and Its Clinical Correlation
Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal·interventional·Posted Jan 13, 2017·Updated Sep 22, 2021
In Brief
A clinical study evaluating Low pressure pneumoperitoneum and standard pneumoperitoneum pressure for Peritoneal Damage. Completed, enrolled 100 participants across 1 site.
Detailed Summary
The investigators hypothesized that applying a low intraperitoneal pressure pneumoperitoneum (≤ 8mmHg) during laparoscopic cholecystectomy, the adverse impact on the surgical peritoneal environment (measured as gene expression of extracellular matrix, adhesion and inflammatory cytokine as well as oxidative stress response and apoptotic index), can be minimized and probably clinical outcomes might be better.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPeritoneal Damage
CountriesSpain
Collaborators--
Timeline
N/ACompletedFinished
2017201820192020202120222023202420252026
First PostedJan 2017
Enrollment StartJan 2017
Primary CompletionApr 2019
TodayJul 2026
First PostedJan 13, 2017
Enrollment StartJan 27, 2017
Primary CompletionApr 28, 2019
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 9.5 years ago
Interventions
Low pressure pneumoperitoneumprocedure
Low pressure pneumoperitoneum
standard pneumoperitoneum pressureprocedure
standard pneumoperitoneum pressure