At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Pasta and Other Durum Wheat-based Products: Effects on Post-prandial Glucose Metabolism
In Brief
A clinical study evaluating Glucose, Semolina soup, and 4 other interventions for Dietary Modification. Completed, enrolled 18 participants across 1 site.
Detailed Summary
Carbohydrate-based products can influence the post-prandial glycemic response differently based on their ability to be digested, absorbed and to affect rises in plasma glucose. Pasta is one of the major carbohydrate-rich foods consumed in Italy. Studies from the literature describe a lower glycemic response after the consumption of pasta compared with other wheat-based products, such as bread. Among the factors affecting post-prandial glycemia after consumption of carbohydrate-based products, the technological process represents a central one.In fact, the different technological processes alter the food matrix which can affect the post-prandial metabolism of glucose differently. Thus, the present study aims at investigating the effect induced by the principal steps of the process of pasta production on the reduction of post-prandial glycemic response (post-prandial glucose, insulin, GLP-1, GIP plasma concentrations).
Study Details
Timeline
Interventions
Glucose monohydrate (55 g) dissolved with 500 mL of water
Semolina soup (322 g) eaten with 500 mL of water
Bread (122 g) eaten with 500 mL of water
Cooked penne (132 g) eaten with 500 mL of water
Cooked penne (142 g) eaten with 500 mL of water
Cooked spaghetti (142 g) eaten with 500 mL of water