At a glance
ClinicalIndex Comparison Record- ✓Age 65 years or older
- ✓Willingness to participate in the study
- ✓Able to answer questions by phone
- ✕Co-enrolled in WHI Memory Study
- ✕Insulin-dependent diabetes
- ✕Unable to complete baseline cognitive assessments
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
COcoa Supplement and Multivitamin Outcomes Study-Mind
In Brief
An observational study for Cognitive Impairment and 2 related conditions. Completed, enrolled 2,262 participants across 1 site.
Detailed Summary
The parent trial (COcoa Supplement and Multivitamin Outcomes Study, COSMOS; NCT02422745) is a randomized clinical trial of cocoa extract supplement (containing a total of 500 mg/d flavanols, including 80 mg. (-)-epicatechins), and a standard multivitamin supplement to reduce the risk of cardiovascular disease and cancer among men aged 60 years and older and women aged 65 years and older. A cognitive ancillary study (COSMOS-Mind) is being conducted among men and women, 65 years and older, who are enrolled in COSMOS and will examine whether the cocoa extract supplement or the multivitamin supplement improves cognitive function and reduces risk of cognitive impairment, including Alzheimer's disease (AD) and other related types of dementia. Participants at the Wake Forest site will only be getting a phone call.