CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 110 enrolled
Drug / intervention
Red-reflex assessment +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03035292
NCT03035292N/ACompleted

Proof of Concept Trial of a Novel Imaging System to Assess and Document Choroidal Reflectance in Children for the Detection of Cataract and Media Opacities.

Cambridge University Hospitals NHS Foundation Trust·observational·Posted Jan 30, 2017·Updated Nov 7, 2023

In Brief

An observational study evaluating Red-reflex assessment and Infrared-reflex assessment for Childhood Cataract. Completed, enrolled 110 participants across 1 site.

Detailed Summary

Sensitivity and specificity of current screening methods for childhood cataracts is poor. This results in delayed diagnosis and management which can decrease the visual prognosis following cataract surgery. It also results in many false positives with resultant unnecessary healthcare costs in specialist paediatric ophthalmology services. This study compares the accuracy of cataract screening using infrared light compared to white light in a population of children attending eye clinic.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesUnited Kingdom
Collaborators--

Timeline

N/ACompletedFinished
2017201820192020202120222023202420252026
First PostedJan 30, 2017
Enrollment StartFeb 1, 2017
Primary CompletionSep 1, 2017
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 9.4 years ago

Interventions

Red-reflex assessmentother

The red reflex was examined in the standard manner using direct ophthalmoscope by medical student examiner

Infrared-reflex assessmentother

The infrared reflex was examined using a modified smart phone camera by a medical student examiner