At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Effects of Choline From Eggs vs. Supplements on the Generation of TMAO in Humans (EGGS)
In Brief
A clinical study evaluating Choline Bitartrate, Pre-cooked, pre-peeled whole hardboiled eggs, and 2 other interventions for Cardiovascular Risk Factor. Completed, enrolled 86 participants across 1 site.
Detailed Summary
The investigators are interested in learning more about choline, a nutrient required by the body. The body does make some choline, but it does not make enough to support health and the rest must be acquired through diet. Eggs, and especially egg yolks, are a major dietary source of choline. Choline can also be given as a dietary supplement. Ingestion of choline supplements has been linked to an increased concentration of a compound called TMAO (trimethylamine N-oxide). Elevated TMAO levels have been linked to higher heart disease risk. With this study, the investigators hope to learn whether there is a difference in the way your body responds to the ingestion of a choline supplement versus the choline found within eggs.
Study Details
Timeline
Interventions
500mg choline bitartrate tablets
Obtained from a commercial source.
Egg whites from pre-cooked, pre-peeled hardboiled eggs. The yolks are removed and discarded.
420 mg phosphatidylcholine capsules obtained from a commercial source.