At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 89 enrolled
Drug / intervention
Low dose of VIS410 +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Phase 2b, Multicenter, Randomized, Double-blind Study to Evaluate the Efficacy and Safety of IV VIS410 in Addition to Oseltamivir Compared With Oseltamivir Alone in Hospitalized Adults With Influenza A Infection Requiring Oxygen Support
In Brief
A Phase 2 clinical trial evaluating Low dose of VIS410, High dose of VIS410, and 1 other intervention for Influenza A. Completed, enrolled 89 participants across 114 sites in 20 countries.
Detailed Summary
This study is to compare the efficacy and safety of VIS410 in combination with oseltamivir vs oseltamivir alone in severely ill subjects with influenza A infection requiring oxygen support.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsInfluenza A
CountriesAustralia, Belarus, Belgium, Bulgaria, Canada, Estonia, France, Georgia, Latvia, Malaysia, New Zealand, Russia, Serbia, Singapore, South Africa, Spain, Thailand, Turkey (Türkiye), Ukraine, United States
Collaborators--
Timeline
Phase 2CompletedFinished
2017201820192020202120222023202420252026
First PostedFeb 2017
Enrollment StartJan 2018
Primary CompletionNov 2018
TodayJul 2026
First PostedFeb 2, 2017
Enrollment StartJan 3, 2018
Primary CompletionNov 22, 2018
TodayJul 2, 2026
Enrollment to primary: 11 monthsPosted 9.4 years ago
Interventions
Low dose of VIS410drug
Single intravenous infusion of fixed low dose of VIS410 in addition to oseltamivir
High dose of VIS410drug
Single intravenous infusion of fixed high dose of VIS410 in addition to oseltamivir
Placebodrug
Single intravenous infusion of placebo in addition to oseltamivir