At a glance
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Effect of Ultraprotective Ventilation on the Lung Inflammatory Response in Patients With Acute Pulmonary Edema Treated With Venoarterial Extracorporeal Oxygenation
In Brief
A clinical study evaluating Ultraprotective ventilation for Cardiogenic Pulmonary Edema and 2 related conditions. Completed, enrolled 20 participants across 1 site.
Detailed Summary
Mechanical ventilation, in spite of being a life-saving technique, can also induce lung injury (VILI) mediated by an inflammatory response, thus having a profound impact in the course of critically ill patients. Ventilatory strategies aimed to minimize this VILI have reduced mortality rates. Patients suffering cardiogenic pulmonary edema may need venoarterial extracorporeal oxygenation, at the same time they are being mechanically ventilated. The objective of this study is to analyze changes induced by the use of utraprotective ventilatory strategies in the inflammatory lung response of these patients and their impact on outcomes.
Study Details
Timeline
Interventions
Adjusting ventilator parameters for 3 ml/kg of tidal volume in order to achieve the ultra protective strategy