CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 20 enrolled
Drug / intervention
brimonidine topical gel 0.33% & survey +1 moredrug
Likely dose
Brimonidine topical gel 0.33%AI-extracted
Key inclusion· 4
  • Age >18 years old
  • Persistent erythema associated with rosacea
  • Investigator Global Assessment score 2–5 (mild to moderate rosacea)
  • Access to computer and internet
Key exclusion· 8
  • Initiation or change in dose of systemic anti-inflammatory medication within 4 weeks of baseline
  • Topical rosacea therapy within 2 weeks of baseline
  • Systemic corticosteroids within 4 weeks of baseline
  • Known allergy or sensitivity to brimonidine topical gel 0.33% or components

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03048058
NCT03048058Phase 4Completed

Internet Surveys and Their Impact on Adherence and Quality of Life to Mirvaso for Rosacea

Wake Forest University Health Sciences·interventional·Posted Feb 9, 2017·Updated Oct 10, 2018

In Brief

A Phase 4 clinical trial evaluating brimonidine topical gel 0.33% & survey and brimonidine topical gel 0.33% & SOC for Rosacea. Completed, enrolled 20 participants across 1 site.

Detailed Summary

An investigator-blinded, prospective, 6 month study of subjects with persistent erythema associated with active rosacea will be conducted in 20 subjects aged 18 years and older. All subjects will receive standard-of-care brimonidine topical gel, 0.33% with instructions to apply it once daily per package insert. Adherence will be assessed using weekly internet surveys to document how often the medication is being used, as well as reminders about rosacea triggers and general use of brimonidine.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsRosacea
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
2017201820192020202120222023202420252026
First PostedFeb 9, 2017
Enrollment StartMay 5, 2016
Primary CompletionJun 1, 2017
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 9.4 years ago

Interventions

brimonidine topical gel 0.33% & surveydrug

The internet survey will ask them how often they have used their medication that week, as well as giving them treatment tips and reminders about rosacea triggers. They will be asked a variety of questions during the weekly internet survey- such as the amount of erythema they currently have (measured by VAS scale), how much burning and stinging they have, how often they have used the medication and where did they apply the medication, as well as any additional side effects they may be having from the medication.

brimonidine topical gel 0.33% & SOCdrug

All subjects will receive standard-of-care brimonidine topical gel 0.33%