CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 70 enrolled
Drug / intervention
Oral glucose tolerance test +2 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03052595
NCT03052595N/ACompleted
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Multiple Sclerosis: The Role of Mitochondrial Dysfunction in Insulin Resistance

Slovak Academy of Sciences·observational·Posted Feb 14, 2017·Updated Apr 12, 2023

In Brief

An observational study evaluating Oral glucose tolerance test, Testing of autonomous nervous system function, and 1 other intervention for Multiple Sclerosis and Mitochondrial Alteration. Completed, enrolled 70 participants across 1 site.

Detailed Summary

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS) and is one of the most common neurological diseases, often leading to disability of the patients. The MS pathogenesis includes vascular and inflammatory components, however recently also the role of mitochondrial dysfunction being a hot topic in neurodegeneration.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsMultiple Sclerosis, Mitochondrial Alteration
CountriesSlovakia
CollaboratorsComenius University

Timeline

N/ACompletedFinished
2017201820192020202120222023202420252026
First PostedFeb 14, 2017
Enrollment StartFeb 1, 2017
Primary CompletionMar 31, 2023
TodayJul 2, 2026
Enrollment to primary: 6.2 yearsPosted 9.4 years ago

Interventions

Oral glucose tolerance testother

Oral glucose tolerance test to measure glucose and insulin concentrations after oral glucose load

Testing of autonomous nervous system functionother

Autonomous nervous system function will be assessed using a battery of tests (orthostasis, Valsalva manoeuvre, heart rate variability recording, blood hormone levels, ect.)

Stroop testother

Stroop test will be used to test cognitive function