CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 15 enrolled
Drug / intervention
Expedited Transport With Mechanical CPRdevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03065647
NCT03065647N/ACompleted
CompareCT.gov

Extracorporeal CPR for Refractory Out-of-Hospital Cardiac Arrest (EROCA)

University of Michigan·interventional·Posted Feb 28, 2017·Updated Jun 3, 2021

In Brief

A clinical study evaluating Expedited Transport With Mechanical CPR for Cardiac Arrest and 8 related conditions. Completed, enrolled 15 participants across 1 site.

Detailed Summary

In the U.S. alone, over 300,000 people per year have sudden out-of-hospital cardiac arrest (OHCA), and less than 1 out of 10 survive. The current standard practice for treating OHCA is to perform cardiopulmonary resuscitation (CPR) and Advanced Cardiovascular Life Support (ACLS) at the scene until either the heart is restarted or resuscitation efforts are considered hopeless and discontinued. An alternative strategy for those with refractory OHCA is expedited transport with ongoing mechanical CPR to an Emergency Department capable of performing extracorporeal cardiopulmonary resuscitation (ECPR). The purpose of study is to test if this strategy is feasible and beneficial.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCardiac Arrest, Heart Arrest, Sudden Cardiac Arrest, Cardiopulmonary Arrest, Death, Sudden, Cardiac, Cardiopulmonary Resuscitation, CPR, Extracorporeal Cardiopulmonary Resuscitation, Extracorporeal Membrane Oxygenation
CountriesUnited States
CollaboratorsNational Heart, Lung, and Blood Institute (NHLBI), Food and Drug Administration (FDA), Physio-Control

Timeline

N/ACompletedFinished
2017201820192020202120222023202420252026
First PostedFeb 28, 2017
Enrollment StartMay 1, 2017
Primary CompletionMar 5, 2020
TodayJul 2, 2026
Enrollment to primary: 2.8 yearsPosted 9.3 years ago

Interventions

Expedited Transport With Mechanical CPRdevice

Patients with OHCA refractory to initial BLS and ACLS will be transported by EMS with ongoing mechanical CPR and ACLS to an emergency department capable of initiating ECPR.