CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 121 enrolled
Drug / intervention
S42909 100 mg +5 moredrug
Likely dose
S42909 100 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03077165
NCT03077165Phase 2Completed
CompareCT.gov

A 10-week Randomized, Double-blind, Placebo-controlled, Prospective, International, Multicentre, Phase IIa Study of S42909 on Leg Ulcer Healing.

Ilkos Therapeutic Inc.·interventional·Posted Mar 10, 2017·Updated Oct 8, 2020

In Brief

A Phase 2 clinical trial evaluating S42909 100 mg, S42909 200 mg, and 4 other interventions for Venous Leg Ulcer. Completed, enrolled 121 participants across 80 sites in 11 countries.

Detailed Summary

Dose-response relationship study of S42909 on leg ulcer healing after oral repeated administration in patients with active venous leg ulcer.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsVenous Leg Ulcer
CountriesArgentina, Austria, Brazil, Canada, Czechia, Hungary, Italy, Poland, Slovakia, Spain, United States
Collaborators--

Timeline

Phase 2CompletedFinished
2017201820192020202120222023202420252026
First PostedMar 10, 2017
Enrollment StartSep 12, 2017
Primary CompletionDec 12, 2019
Study CompletionJan 22, 2020
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 9.3 years ago

Interventions

S42909 100 mgdrug

50 mg Film-coated tablets per os administration, twice a day taken at the end of the morning and at evening meals.

S42909 200 mgdrug

50 mg Film-coated tablets per os administration, twice a day taken at the end of the morning and at evening meals.

S42909 400 mgdrug

200 mg Film-coated tablets per os administration, twice a day taken at the end of the morning and at evening meals.

S42909 800 mgdrug

200 mg Film-coated tablets per os administration,twice a day taken at the end of the morning and at evening meals.

S42909 1200 mgdrug

200 mg Film-coated tablets per os administration, twice a day taken at the end of the morning and at evening meals.

Placebo Oral Tabletdrug

Matching placebo tablets, per os administration, twice a day taken at the end of the morning and at evening meals.