CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 10 enrolled
Drug / intervention
Holding during coolingother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03079284
NCT03079284N/ACompleted

The Effects of Holding on Stress and Bonding in Mother-Infant Dyads During Therapeutic Hypothermia

Alexa Craig·interventional·Posted Mar 14, 2017·Updated Sep 4, 2025

In Brief

A clinical study evaluating Holding during cooling for Hypoxic-Ischemic Encephalopathy. Completed, enrolled 10 participants across 1 site.

Detailed Summary

Ten infants undergoing therapeutic hypothermia for hypoxic-ischemic encephalopathy will be enrolled in a new protocol that will allow mothers to hold their infants during the hypothermia treatment period. This is a safety study that will assess whether or not there is an increase in adverse event frequency in infants that are held during hypothermia. Parents and NICU nurses will be given a questionnaire after holding is complete investigating their feelings on maternal-infant bonding and safety of the holding protocol.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
CollaboratorsMaineHealth

Timeline

N/ACompletedFinished
2017201820192020202120222023202420252026
First PostedMar 14, 2017
Enrollment StartMar 20, 2017
Primary CompletionSep 23, 2017
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 9.3 years ago

Interventions

Holding during coolingother

An initial set of vital sings will be recorded before the infant is removed from the isolette. The mother will sit in a reclining chair next to the isolette and place a thermal barrier over her chest and abdomen. The infant will be transferred to the mother by placing the hands under the cooling blanket so as to move the infant and cooling blanket together as one unit. The mother will be allowed to hold for thirty minutes provided that the infant's temperature does not increase by greater than one degree centigrade and the oxygen saturation does not drop below 90%. After thirty minutes, the infant will be returned to the isolette.