CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 449 enrolled
Drug / intervention
Placebo +1 moredrug
Likely dose
Brivaracetam 25 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03083665
NCT03083665Phase 3Completed

A Randomized, Double-blind, Placebo-controlled, Multicenter, Parallel-group Study to Evaluate the Efficacy and Safety of Adjunctive Brivaracetam in Subjects (>=16 to 80 Years of Age) With Partial Seizures With or Without Secondary Generalization

UCB Biopharma SRL·interventional·Posted Mar 20, 2017·Updated Oct 14, 2025

In Brief

A Phase 3 clinical trial evaluating Placebo and Brivaracetam for Partial Seizures With or Without Secondary Generalization and Epilepsy. Completed, enrolled 449 participants across 94 sites in 7 countries.

Detailed Summary

The purpose of the study is to evaluate the efficacy of brivaracetam (BRV) compared to placebo (PBO) as adjunctive treatment in subjects (\>=16 to 80 years of age) with partial seizures with or without secondary generalization despite current treatment with 1 or 2 concomitant antiepileptic drugs (AEDs) and to assess the safety and tolerability of BRV in subjects \>= 16 years to 80 years of age.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChina, Japan, Malaysia, Philippines, Singapore, Taiwan, Thailand
Collaborators--

Timeline

Phase 3CompletedFinished
2017201820192020202120222023202420252026
First PostedMar 20, 2017
Enrollment StartAug 22, 2017
Primary CompletionJun 30, 2022
TodayJul 2, 2026
Enrollment to primary: 4.9 yearsPosted 9.3 years ago

Interventions

Placebodrug

* Pharmaceutical form: Film-coated tablets * Route of administration: Oral use

Brivaracetamdrug

* Pharmaceutical form: Film-coated tablets * Concentration: 25 mg tablets and 50 mg tablets * Route of administration: Oral use