CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 14 enrolled
Drug / intervention
Cigaretteother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03086707
NCT03086707N/ACompleted
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A Two-arm, Open Label, Prefatory Study to Explore Changes in Nasal Mucociliary Clearance Between Smokers and Never Smokers and to Standardize Nasal Scraping Procedure

Philip Morris Products S.A.·interventional·Posted Mar 22, 2017·Updated Nov 20, 2020

In Brief

A clinical study evaluating Cigarette for Smokers and Never Smokers. Completed, enrolled 14 participants across 2 sites.

Detailed Summary

This study intends to evaluate the nasal mucociliary clearance (NMC) by determining the value obtained for saccharin transit time (STT) test over the course of 12 hours following a single cigarette use in adult smokers, to compare it relative to never smokers, and to examine the relationship between plasma nicotine levels and STT value in smokers and never smokers. Safety will also be monitored during the study. The planned maximum study duration for a single study participant from Screening through completion of study will be 33 days.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSmokers, Never Smokers
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2017201820192020202120222023202420252026
First PostedMar 22, 2017
Enrollment StartJan 21, 2017
Primary CompletionAug 14, 2017
Study CompletionSep 29, 2017
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 9.3 years ago

Interventions

Cigaretteother

After enrollment, and between Visit 2 and Visit 3, the subjects will abstain from smoking for a period of 8 hours. At Visit 3, after the 8-hour smoking abstinence period, the subjects will smoke 1 single cigarette.