CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 15 enrolled
Drug / intervention
Definity, (Lipid Microspheres) Intravenous Suspension +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03092089
NCT03092089Phase 2Completed
CompareCT.gov

Sonothrombolysis in Patients With an ST-segment Elevation Myocardial Infarction. A Prospective Single-arm Study.

Harald Becher·interventional·Posted Mar 27, 2017·Updated Jun 9, 2021

In Brief

A Phase 2 clinical trial evaluating Definity, (Lipid Microspheres) Intravenous Suspension, Myocardial Contrast Echocardiography, and 1 other intervention for ST-segment Elevation Myocardial Infarction. Completed, enrolled 15 participants across 1 site.

Detailed Summary

This study evaluates what effect sonothrombolysis may have on spontaneous reperfusion, microvascular obstruction, left ventricular function and infarct size in patients presenting with their first ST-segment Elevation Myocardial Infarction.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsST-segment Elevation Myocardial Infarction
CountriesCanada
CollaboratorsAlberta Health services, University of Alberta

Timeline

Phase 2CompletedFinished
2017201820192020202120222023202420252026
First PostedMar 27, 2017
Enrollment StartAug 15, 2017
Primary CompletionOct 3, 2019
TodayJul 2, 2026
Enrollment to primary: 2.1 yearsPosted 9.3 years ago

Interventions

Definity, (Lipid Microspheres) Intravenous Suspensiondrug

Sonothrombolysis (High Impulse therapeutic ultrasound with infusion of ultrasound contrast agent Definity) will be applied before and after standard of care reperfusion therapy with PPCI

Myocardial Contrast Echocardiographydevice

Myocardial contrast echocardiography will be applied before standard of care reperfusion therapy as well as prior to discharge and at 3 month follow up

Repurfusion therapy with PPCIprocedure

Patients will receive reperfusion therapy with PPCI as standard of care