At a glance
ClinicalIndex Comparison Record- ✓Healthy volunteer aged 18–65 years
- ✕Known underlying cardiac or pulmonary disease
- ✕Active respiratory infections
- ✕Previous inability to tolerate noninvasive positive pressure ventilation with addition of a nasal cannula
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Analysis of Preoxygenation Combining Nasal Cannula With Noninvasive Positive Pressure Ventilation: A Randomized Crossover Trial
In Brief
A clinical study evaluating Ventilation with nasal cannula and Ventilation without nasal cannula for Hypoxia. Completed, enrolled 37 participants across 1 site.
Detailed Summary
This is a prospective randomized cross over study of healthy volunteers comparing end-tidal oxygen concentration among subjects undergoing continuous positive airway pressure ventilation via a noninvasive ventilation (NIV) mask with and without the addition of nasal cannulas.
Study Details
Timeline
Interventions
Subject is fitted with a face mask and undergoes three continuous minutes of positive pressure ventilation (Respironics AF521, EE with CapStrap headgear) while simultaneously wearing nasal cannula (Carefusion AirLife Standard Nasal Cannula) with 15 L/min oxygen flow. Subject then removes mask and immediately exhales into an oxygen sensor (Maxtec Max-250E).
Subject is fitted with a face mask and undergoes three continuous minutes of positive pressure ventilation (Respironics AF521, EE with CapStrap headgear). Subject then removes mask and immediately exhales into an oxygen sensor (Maxtec Max-250E).