CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 40 enrolled
Drug / intervention
S-equol and Placebo +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03101085
NCT03101085Phase 2Completed

S-Equol in Alzheimer's Disease 2 (SEAD2) Trial

Russell Swerdlow·interventional·Posted Apr 4, 2017·Updated Jul 25, 2024

In Brief

A Phase 2 clinical trial evaluating S-equol and Placebo and Placebo and S-equol for Alzheimer Disease. Completed, enrolled 40 participants across 2 sites.

Detailed Summary

By doing this study researchers hope to learn if S-equol, a compound that acts like estrogen in the body, causes an increase in mitochondrial activity. Researchers also hope to determine the safety and tolerability of a therapeutic dose of S-equol and whether or not it influences cognition.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 2CompletedFinished
2017201820192020202120222023202420252026
First PostedApr 4, 2017
Enrollment StartMay 5, 2017
Primary CompletionMar 1, 2021
TodayJul 2, 2026
Enrollment to primary: 3.8 yearsPosted 9.2 years ago

Interventions

S-equol and Placebodrug

S-equol is an estrogen receptor β (ERβ) agonist. Provided in capsules. The placebo is a matched pill that cannot be distinguished from the active S-equol.

Placebo and S-equoldrug

S-equol is an estrogen receptor β (ERβ) agonist. Provided in capsules. The placebo is a matched pill that cannot be distinguished from the active S-equol.