CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 75 enrolled
Drug / intervention
1% Lidocaine +2 moredrug
Likely dose
10 mL of 1% lidocaine, OR 10 mL of 0.25% bupivacaine, OR 5 mL of 1% lidocaine plus 5 mL of 0.25% bupivacaine administered epidurallyAI-extracted
Key inclusion· 3
  • ✓Pregnant patients over age 19
  • ✓Scheduled for labor induction
  • ✓Requesting epidural analgesia
Key exclusion· 8
  • ✕Age less than 19 years
  • ✕Allergy to lidocaine, bupivacaine, or related local anesthetics
  • ✕Preexisting neuropathy
  • ✕History of back pain prior to pregnancy or back surgery

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03103100
NCT03103100Phase 3Completed
CompareCT.gov

Comparing Bupivacaine, Lidocaine, and a Combination of Bupivacaine and Lidocaine for Labor Epidural Activation: A Prospective, Randomized, Double-Blind Study

University of Alabama at Birmingham·interventional·Posted Apr 6, 2017·Updated Aug 31, 2020

In Brief

A Phase 3 clinical trial evaluating 1% Lidocaine, 0.25% Bupivacaine, and 1 other intervention for Labor Pain. Completed, enrolled 75 participants across 1 site.

Detailed Summary

This study will compare and determine the most ideal local anesthetic (LA) solution to activate a labor epidural: lidocaine, bupivacaine, or a combination of bupivacaine plus lidocaine.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsLabor Pain
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
20162017201820192020202120222023202420252026
First PostedApr 6, 2017
Enrollment StartOct 8, 2015
Primary CompletionJul 1, 2019
Study CompletionSep 9, 2019
TodayJul 2, 2026
Enrollment to primary: 3.7 yearsPosted 9.2 years ago

Interventions

1% Lidocainedrug

10 mL of 1% lidocaine

0.25% Bupivacainedrug

10 mL of 0.25% bupivacaine

Bupivacaine plus Lidocainedrug

5 mL of 1% lidocaine and 5 mL of 0.25% bupivacaine