CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 91 enrolled
Drug / intervention
Prototype nasal dilator strip +1 moredevice
Likely dose
Prototype nasal dilator strip (GSK AB 2R11) applied daily from Day 1 to Day 28, then on Day 29 or 30AI-extracted
Key inclusion· 3
  • Nostril types I and II (inter-axial angle <41° for type I, 41–70° for type II)
  • Chronic nocturnal nasal congestion ('always or almost always') for at least the last year
  • Reports trouble with sleep
Key exclusion· 16
  • Known or suspected intolerance/hypersensitivity to latex or study materials; allergy to adhesive bandages
  • Chronic skin condition or eczema on face or nose
  • Visible open sores, sunburn, or irritation on face or nose immediately prior to treatment
  • Severe obstructive sleep apnea/hypopnea syndrome with AHI ≥30 events/hour at baseline

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03105297
NCT03105297Phase 2Completed

An Exploratory Study of a Nasal Dilator Strip

GlaxoSmithKline·interventional·Posted Apr 7, 2017·Updated Jul 26, 2019

In Brief

A Phase 2 clinical trial evaluating Prototype nasal dilator strip and No strip for Sleep Disordered Breathing and Congestion, Nasal. Completed, enrolled 91 participants across 1 site.

Detailed Summary

To characterize the performance of the nasal dilator strip in lowering nasal resistance during sleep, promoting nasal route breathing and reducing the signs and symptoms of sleep disordered breathing in a group of chronic nocturnal nasal congestion sufferers who report trouble with their sleep.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia
Collaborators--

Timeline

Phase 2CompletedFinished
20102011201220132014201520162017201820192020202120222023202420252026
First PostedApr 7, 2017
Enrollment StartSep 25, 2009
Primary CompletionAug 10, 2010
TodayJul 2, 2026
Enrollment to primary: 11 monthsPosted 9.2 years ago

Interventions

Prototype nasal dilator stripdevice

External Prototype Nasal Dilator strip. GSK prototype nasal dilator AB 2R11. All the participants used nasal dilator strip throughout the active phase of the study (Day 1 to Day 28). Followed by that all the participants used the nasal strip on Day 29 or 30 in Nasal resistance phase of the study as per their randomization sequence.

No stripother