At a glance
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Perioperative Hypothermia and Myocardial Injury After Non-cardiac Surgery
In Brief
A clinical study evaluating aggressive warming and routine thermal management for Perioperative Care and 3 related conditions. Completed, enrolled 5,056 participants across 11 sites in 2 countries.
Detailed Summary
We propose to test the hypothesis that aggressive warming reduces the incidence of major cardiovascular complications, compared to routine care. Half of the participants will be randomly assigned to routine care (core temperature ≈35.5°C), while the other half will receive aggressive warming (\>37°C core temperature) in a multi-center trial.
Study Details
Timeline
Interventions
Patients will be pre-warming 30 minutes before induction of anesthesia and aggressively warmed during surgery to a target intraoperative core temperature between 37 and 37.5°C.
A forced-air cover will be positioned but will not initially be activated. The warmer will be activated when core temperature decrease to 35.5°C.