At a glance
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Exercise to Improve Hippocampal Connectivity and Learning in Older Adults
In Brief
A clinical study evaluating Cardiorespiratory fitness training and Functional fitness training for Sedentary Lifestyle. Completed, enrolled 122 participants across 1 site.
Detailed Summary
Given the accelerating growth of older adults worldwide and the decline in cognitive function with aging, therapeutics that remediate age-related cognitive decline are needed more than ever. The proposed research seeks to better understand and enhance the detection of exercise effects on hippocampal network function and learning and memory, which decline with aging and Alzheimer's. Success would lead to new ways to detect benefits of exercise on cognitive aging and would lead to mechanistic insight on how such plasticity is possible while also informing prevention strategies.
Study Details
Timeline
Interventions
Physical exercise of moderate intensity designed to improve cardiorespiratory fitness
Physical exercise of light intensity designed to improve functional fitness