At a glance
ClinicalIndex Comparison RecordPhase 4Completed· 60 enrolled
Drug / intervention
Melatonin +2 moredrug
Likely dose
Melatonin 6mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
The Protective Effect of Melatonin in Patients Under Carotid Endarterectomy
In Brief
A Phase 4 clinical trial evaluating Melatonin, placebo, and 1 other intervention for Carotid Stenosis. Completed, enrolled 60 participants across 1 site.
Detailed Summary
The main purpose of this study is to evaluate the effects of melatonin in the regulation of the vascular injury in patients under carotid endarterectomy through population-based, randomized, double-blind, placebo-controlled trial.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCarotid Stenosis
CountriesChina
Collaborators--
Timeline
Phase 4CompletedFinished
2017201820192020202120222023202420252026
Enrollment StartJun 2016
First PostedApr 2017
Primary CompletionJun 2017
Study CompletionNov 2017
TodayJul 2026
First PostedApr 14, 2017
Enrollment StartJun 1, 2016
Primary CompletionJun 1, 2017
Study CompletionNov 1, 2017
TodayJul 2, 2026
Enrollment to primary: 1 yearPosted 9.2 years ago
Interventions
Melatonindrug
Patients under CEA taking 6mg/day melatonin orally from 3 days before operation to 3 days after operation.
placebodrug
Patients under CEA taking placebo orally from 3 days before operation to 3 days after operation.
blankother
Patients under CEA without taking melatonin or placebo