CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 21 enrolled
Drug / intervention
Anodal cerebellar and cathodal spinal tDCS +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03120013
NCT03120013N/ACompleted
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Rehabilitative Trial With Cerebello-Spinal tDCS for the Treatment of Neurodegenerative Ataxia

Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia·interventional·Posted Apr 19, 2017·Updated Mar 3, 2020

In Brief

A clinical study evaluating Anodal cerebellar and cathodal spinal tDCS and Sham cerebellar and sham spinal tDCS for Ataxia, Cerebellar and 10 related conditions. Completed, enrolled 21 participants across 1 site.

Detailed Summary

Neurodegenerative cerebellar ataxias represent a group of disabling disorders for which we currently lack effective therapies. Cerebellar transcranial direct current stimulation (tDCS) is a non-invasive technique, which has been demonstrated to modulate cerebellar excitability and improve symptoms in patients with cerebellar ataxias. In this randomized, double-blind, sham-controlled study, the investigators will evaluate whether a two-weeks' treatment with cerebellar anodal tDCS and spinal cathodal tDCS can improve symptoms in patients with neurodegenerative cerebellar ataxia and can modulate cerebello-motor connectivity, at short and long term.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAtaxia, Cerebellar, Cerebellar Ataxia, Spinocerebellar Ataxias, Ataxia, Spinocerebellar, Spinocerebellar Ataxia Type 1, Spinocerebellar Ataxia Type 2, Spinocerebellar Ataxia 3, Spinocerebellar Degenerations, Friedreich Ataxia, Ataxia With Oculomotor Apraxia, Multiple System Atrophy
CountriesItaly
Collaborators--

Timeline

N/ACompletedFinished
2017201820192020202120222023202420252026
First PostedApr 19, 2017
Enrollment StartFeb 6, 2017
Primary CompletionDec 1, 2018
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 9.2 years ago

Interventions

Anodal cerebellar and cathodal spinal tDCSdevice

10 sessions of anodal cerebellar and cathodal spinal transcranial direct current stimulation (5 days/week for 2 weeks)

Sham cerebellar and sham spinal tDCSdevice

10 sessions of sham cerebellar and sham spinal transcranial direct current stimulation (5 days/week for 2 weeks)