CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 10 enrolled
Drug / intervention
Lavage with Platelet Poor Plasma (PPP)biological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03120988
NCT03120988Phase 1Completed
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Assessing Catabolic Marker Levels in the Knee Synovial Fluid Microenvironment After Lavage With Platelet Poor Plasma (PPP)

Regenexx, LLC·interventional·Posted Apr 19, 2017·Updated Jul 17, 2019

In Brief

A Phase 1 clinical trial evaluating Lavage with Platelet Poor Plasma (PPP) for Knee Osteoarthritis. Completed, enrolled 10 participants across 1 site.

Detailed Summary

The purpose of this study is to understand how the components of osteoarthritic knee joint fluid (synovial fluid) change after lavage treatment with platelet poor plasma. Additionally, the study participants will complete outcome questionnaire surveys before and after the treatment in conjunction with when synovial fluid is removed from the knee (2, 4, and 6 weeks after lavage). This data will help determine if the treatment of an osteoarthritic knee joint with platelet poor plasma lavage is a suitable stand-alone therapy or to improve outcome by preparing a patient's knee for further regenerative therapies.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsKnee Osteoarthritis
CountriesUnited States
Collaborators--

Timeline

Phase 1CompletedFinished
2017201820192020202120222023202420252026
First PostedApr 19, 2017
Enrollment StartJul 1, 2016
Primary CompletionJun 30, 2017
Study CompletionDec 1, 2017
TodayJul 2, 2026
Enrollment to primary: 12 monthsPosted 9.2 years ago

Interventions

Lavage with Platelet Poor Plasma (PPP)biological

Lavage of 50cc PPP