At a glance
ClinicalIndex Comparison RecordN/ACompleted· 375 enrolled
Drug / intervention
timing for oocyte denudation and Intracytoplasmatic Sperm injectionprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Effect of Timing of Oocyte Denudation Before ICSI and Its Results in an Oocyte Donation Model: a Cluster Randomized Controlled Clinical Trial
In Brief
A clinical study evaluating timing for oocyte denudation and Intracytoplasmatic Sperm injection for Fertility. Completed, enrolled 375 participants across 1 site.
Detailed Summary
Analyze the effect of preincubation time of oocyte on the results of ICSI in a oocyte donation model.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsFertility
CountriesArgentina
Collaborators--
Timeline
N/ACompletedFinished
20162017201820192020202120222023202420252026
Enrollment StartDec 2015
First PostedApr 2017
Primary CompletionDec 2018
Study CompletionAug 2019
TodayJul 2026
First PostedApr 20, 2017
Enrollment StartDec 1, 2015
Primary CompletionDec 1, 2018
Study CompletionAug 1, 2019
TodayJul 2, 2026
Enrollment to primary: 3 yearsPosted 9.2 years ago
Interventions
timing for oocyte denudation and Intracytoplasmatic Sperm injectionprocedure
Donated oocytes were randomly allocated to two groups concerning the time of cumulus corona removal. The first group: After oocyte retrieval, cumulus cells were immediately removed and then ICSI was performed; in the second group, the oocyte-cumulus complexes were incubated for 4 hours. Afterwards, the granulosa cells were removedand ICSI was immediately performed.