CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 39 enrolled
Drug / intervention
Methylprednisolonedrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03122847
NCT03122847N/ACompleted

The Effect of 4.5 Gram Methylprednisolone Administered Once Weekly for 12 Weeks on Bone Metabolism in Graves´ Ophthalmopathy

Torben Harsløf·observational·Posted Apr 21, 2017·Updated Mar 19, 2025

In Brief

An observational study evaluating Methylprednisolone for Graves Ophthalmopathy. Completed, enrolled 39 participants across 2 sites.

Detailed Summary

Continuous use of systemic glucocorticoids decreases bone mineral density and increases fracture risk. Graves' orbitopathy is treated with weekly infusion of high-dose intravenous glucocorticoid. The investigators aim at investigating whether this treatment regimen also affects bone metabolism.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesDenmark

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedApr 21, 2017
Enrollment StartJun 7, 2017
Primary CompletionJul 14, 2022
Study CompletionFeb 1, 2024
TodayJul 2, 2026
Enrollment to primary: 5.1 yearsPosted 9.2 years ago

Interventions

Methylprednisolonedrug

Intravenous methylprednisolone