CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 57 enrolled
Drug / intervention
LUM/IVAdrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03125395
NCT03125395Phase 3Completed

A Phase 3, Rollover Study to Evaluate the Safety of Long-term Treatment With Lumacaftor/Ivacaftor Combination Therapy in Subjects Aged 2 Years and Older With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation

Vertex Pharmaceuticals Incorporated·interventional·Posted Apr 24, 2017·Updated Aug 7, 2020

In Brief

A Phase 3 clinical trial evaluating LUM/IVA for Cystic Fibrosis. Completed, enrolled 57 participants across 20 sites in 2 countries.

Detailed Summary

A Rollover Safety Study of Lumacaftor/Ivacaftor in Subjects Aged 2 Years and Older With Cystic Fibrosis, Homozygous for F508del.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCystic Fibrosis
CountriesCanada, United States
Collaborators--

Timeline

Phase 3CompletedFinished
201820192020202120222023202420252026
First PostedApr 24, 2017
Enrollment StartMay 12, 2017
Primary CompletionJul 17, 2019
TodayJul 2, 2026
Enrollment to primary: 2.2 yearsPosted 9.2 years ago

Interventions

LUM/IVAdrug

Participants received LUM/IVA every q12h.