At a glance
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Neural Mechanisms of Monoaminergic Engagement in Late-life Depression Treatment Response (NEMO)
In Brief
A Phase 4 clinical trial evaluating Escitalopram Pill, Placebo, and 1 other intervention for Major Depressive Disorder. Completed, enrolled 57 participants across 1 site.
Detailed Summary
The Department of Psychiatry at the University of Pittsburgh is conducting a research study to learn about the changes that occur in the brain when individuals suffer from and then are treated for depression. The NEMO study has two main purposes. The first is to provide medication treatment to individuals ages 60 and older who are currently depressed. The second part of the study involves completing a series of 4 MRIs, which assess changes in brain function over the course of treatment. This research may help investigators to develop faster and more effective treatment plans in the future, as brain responses that are detected early in treatment may predict how well an individual will respond to antidepressant medication.
Study Details
Timeline
Interventions
Double-blinded, randomly assigned
Double-blinded, randomly assigned
Double-blinded, randomly assigned