CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 101 enrolled
Drug / intervention
Acetaminophendrug
Likely dose
Acetaminophen 1000 mgAI-extracted
Key inclusion· 1
  • Adult patients undergoing Mohs micrographic surgery for non-melanoma skin cancers
Key exclusion· 3
  • History of liver transplant, hepatitis, or cirrhosis
  • Required to be NPO for subsequent closure by other surgical specialties
  • Known allergy to acetaminophen

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03131713
NCT03131713Phase 3Completed

Impact of Preoperative Acetaminophen and Carbohydrate Loading to on Pain and Functional Status in Patients Undergoing Mohs Micrographic Surgery for Non-melanoma Skin Cancers

Tufts Medical Center·interventional·Posted Apr 27, 2017·Updated Oct 7, 2019

In Brief

A Phase 3 clinical trial evaluating Acetaminophen for Non-melanoma Skin Cancer. Completed, enrolled 101 participants across 1 site.

Detailed Summary

The study's goal is to assess impact of preoperative acetaminophen and oral carbohydrate drinks on pain and functional status experienced by patients undergoing Mohs micrographic surgery for non-melanoma skin cancers. Patients are randomly assigned to receive standard of care or preoperative acetaminophen 1000 mg and Gatorade sports drinks 2 packets before surgery. Patients are then asked to rate their level of pain, anxiety, thirst, hunger, fatigue on a scale of 0-100 on day of surgery before surgery has started, after clearance of skin cancer, and at the end of the visit. Patients are contacted by phone 48 hours after their surgery to assess their maximum level of post-operative pain (rated from 0-100), usage of over the counter or prescribed pain medications, and presence of complications e.g. bleeding, infection, dehiscence. Differences in perioperative functional status and pain medication usage are compared between patients in control and intervention groups.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
2017201820192020202120222023202420252026
First PostedApr 27, 2017
Enrollment StartJul 1, 2016
Primary CompletionDec 31, 2017
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 9.2 years ago

Interventions

Acetaminophendrug

Acetaminophen 1000mg