CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 34 enrolled
Drug / intervention
Zinc Acetate 50 Mg Oral Capsule +1 moredrug
Likely dose
Zinc Acetate 50 Mg Oral Capsulefrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03135522
NCT03135522Phase 2Completed
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Pilot of Zinc Acetate to Improve Chronic Cough

Johns Hopkins University·interventional·Posted May 1, 2017·Updated Jan 20, 2021

In Brief

A Phase 2 clinical trial evaluating Zinc Acetate 50 Mg Oral Capsule and Placebo oral capsule for Cough. Completed, enrolled 34 participants across 5 sites.

Detailed Summary

The Pilot of Zinc Acetate to Improve Chronic Cough (ZICO) is a study of 36 patients with chronic refractory cough that will be used to (1) assess if zinc acetate (150 mg/day) will improve patient reported measures of cough, (2) to establish if treatment with zinc acetate is well tolerated, and (3) to determine if the trial logistics are feasible.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCough
CountriesUnited States
CollaboratorsNational Heart, Lung, and Blood Institute (NHLBI), American Lung Association

Timeline

Phase 2CompletedFinished
201820192020202120222023202420252026
First PostedMay 1, 2017
Enrollment StartFeb 14, 2018
Primary CompletionDec 11, 2019
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 9.2 years ago

Interventions

Zinc Acetate 50 Mg Oral Capsuledrug

* Day 0 (randomization) to day 3 Zinc acetate 50 mg per day (one capsule) * Day 4 to day 7 If well tolerated: Zinc acetate 100 mg per day (two capsules) * Day 8 to V5 (6 weeks) If well tolerated: Zinc acetate 150 mg per day (three capsules)

Placebo oral capsuledrug

* Day 0 (randomization) to day 3 Placebo (one capsule per day) * Day 4 to day 7 If well tolerated: placebo (two capsules per day) * Day 8 to V5 (6 weeks) If well tolerated: placebo (three capsules per day)