CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 59 enrolled
Drug / intervention
Spesolimab (low dose) +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03135548
NCT03135548Phase 2Completed

Multi-center, Double-blind, Randomised, Placebo-controlled, Phase IIa Study to Investigate Efficacy, Safety, Tolerability, Pharmacokinetics and Pharmacogenomics of Multiple Intravenous Doses of BI 655130 in Patients With Palmoplantar Pustulosis (PPP)

Boehringer Ingelheim·interventional·Posted May 1, 2017·Updated Oct 16, 2025

In Brief

A Phase 2 clinical trial evaluating Spesolimab (low dose), Placebo, and 1 other intervention for Psoriasis. Completed, enrolled 59 participants across 18 sites in 6 countries.

Detailed Summary

The primary objective of this trial is to investigate the safety and efficacy of BI 655130 in patients with PPP following multiple intravenous administrations compared to placebo.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPsoriasis
CountriesCanada, Denmark, Germany, Italy, Spain, Sweden
Collaborators--

Timeline

Phase 2CompletedFinished
201820192020202120222023202420252026
First PostedMay 1, 2017
Enrollment StartMay 30, 2017
Primary CompletionJul 12, 2018
Study CompletionNov 14, 2018
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 9.2 years ago

Interventions

Spesolimab (low dose)drug

12 weeks treatment

Placebodrug

12 weeks treatment

Spesolimab (high dose)drug

12 weeks treatment