CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 30 enrolled
Drug / intervention
PRP +2 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03136965
NCT03136965Phase 2Completed
CompareCT.gov

Platelet-Rich Plasma (PRP) Therapy for Patellar Tendinopathy: A Randomized Controlled Trial Correlating Clinical, Biomechanical and Novel Imaging Biomarkers

University of Wisconsin, Madison·interventional·Posted May 2, 2017·Updated Oct 26, 2023

In Brief

A Phase 2 clinical trial evaluating PRP, Dry Needling, and 1 other intervention for Patellar Tendinitis. Completed, enrolled 30 participants across 1 site.

Detailed Summary

The overall goal of this research is to find an effective treatment for patellar tendinopathy (PT). To achieve this, we will conduct a double-blinded randomized controlled trial to investigate if platelet-rich plasma is effective for treatment. Clinical (pain and function scores) and bio-mechanical (knee strength) measures will be correlated with disease modification changes assessed using conventional and novel quantitative magnetic resonance imaging (MRI) and ultrasound (US) techniques.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPatellar Tendinitis
CountriesUnited States
CollaboratorsGeneral Electric

Timeline

Phase 2CompletedFinished
201820192020202120222023202420252026
First PostedMay 2, 2017
Enrollment StartApr 25, 2017
Primary CompletionAug 15, 2022
TodayJul 2, 2026
Enrollment to primary: 5.3 yearsPosted 9.2 years ago

Interventions

PRPbiological

Injection of autologous platelet rich plasma (PRP)

Dry Needlingprocedure

This is a therapeutic procedure that involves the same injection procedures under ultrasound guidance as in the PRP group but no PRP will be injected inside the patellar tendon.

Dry Needling - Shamprocedure

This is a sham procedure that involves similar injection procedures under ultrasound guidance as in the PRP and DN groups with no injection of PRP or needle placement inside the patellar tendon.