CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 36 enrolled
Drug / intervention
Temozolomide +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03139916
NCT03139916Phase 2Completed

Phase II Clinical Trial of Bavituximab With Radiation and Temozolomide for Patients With Newly Diagnosed Glioblastoma

Massachusetts General Hospital·interventional·Posted May 4, 2017·Updated May 16, 2024

In Brief

A Phase 2 clinical trial evaluating Temozolomide, Bavituximab, and 1 other intervention for Glioblastoma. Completed, enrolled 36 participants across 2 sites.

Detailed Summary

This research study is studying a combination of drugs with radiation as a possible treatment for Glioblastoma. The drugs involved in this study are: * Bavituximab * Temozolomide

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsGlioblastoma
CountriesUnited States

Timeline

Phase 2CompletedFinished
201820192020202120222023202420252026
First PostedMay 4, 2017
Enrollment StartSep 13, 2017
Primary CompletionAug 31, 2022
TodayJul 2, 2026
Enrollment to primary: 5.0 yearsPosted 9.2 years ago

Interventions

Temozolomidedrug

Temozolomide causes cell death and shrinks and kills the cancer cells

Bavituximabdrug

Bavituximab may activate (cause) the immune system to attack the cancer cells

Radiationradiation

Radiation causes cell death and shrinks and kills the cancer cells.