CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 20 enrolled
Drug / intervention
aPTT guided heparin management +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03143569
NCT03143569N/ACompleted

Ventricular Assist Device Anti-Factor Xa (VAD ANTIX) Monitoring Study: a Prospective Randomized Feasibility Trial

Washington University School of Medicine·interventional·Posted May 8, 2017·Updated Feb 25, 2020

In Brief

A clinical study evaluating aPTT guided heparin management and Anti-factor Xa guided heparin management for Left Sided Heart Failure and 7 related conditions. Completed, enrolled 20 participants across 1 site.

Detailed Summary

This study evaluates two different methods for monitoring a patient's anti-clotting \[heparin\] therapy after they receive a heart pump implant \[left ventricular assist device -LVAD\]. One method tests for how long it takes the patient's blood to clot and uses that to determine if they are on the right dose of heparin. The other method uses a more direct measure of how much heparin is in the blood. The hypothesis is that the method that more directly measures how much heparin is in the patient's blood will provide better medical results for the patient's care after they have the heart pump implant. To that end, the investigators are conducting this feasibility trial to establish the logistics associated with the implementation of these heparin monitoring approaches.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedMay 8, 2017
Enrollment StartMay 20, 2017
Primary CompletionJul 12, 2018
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 9.2 years ago

Interventions

aPTT guided heparin managementdevice

post-surgical implantation anti-coagulation therapy to prevent clotting in ventricular assist device.

Anti-factor Xa guided heparin managementdevice

post-surgical implantation anti-coagulation therapy to prevent clotting in ventricular assist device