CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 43 enrolled
Drug / intervention
The Modular Protocol for Mental Health +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03143634
NCT03143634Phase 2Completed

The Modular Protocol for Mental Health (MPMH): A Pilot Randomised Clinical Trial of a Transdiagnostic Psychological Treatment for Mood and Anxiety Disorders in Adults

Medical Research Council Cognition and Brain Sciences Unit·interventional·Posted May 8, 2017·Updated Sep 29, 2020

In Brief

A Phase 2 clinical trial evaluating The Modular Protocol for Mental Health and Treatment-as-usual for Major Depressive Disorder and 7 related conditions. Completed, enrolled 43 participants across 1 site.

Detailed Summary

Currently, our best psychological treatments for anxiety and mood disorders only focus on individual diagnoses. So, there are separate treatments for Panic Disorder, or Depressive Disorder, or Social Anxiety, etc. These 'diagnosis-specific' treatments work well for people whose problems fit neatly into a single diagnosis. However, they work far less well for people with complex problems involving multiple diagnoses, and 50% of patients fail to respond well to these existing treatments. The purpose of this study is to test a new psychological treatment for anxiety and mood problems (the Modular Protocol for Mental Health \[MPMH\]). Instead of focusing on any single diagnosis, MPMH combines the best treatment techniques into 10 modules to target problems common across all of the different mood and anxiety diagnoses (e.g., intense emotions, negative thinking, upsetting memories, distressing habits). MPMH should therefore be a better treatment for the large numbers of individuals whose problems do not fit neatly into a single diagnosis and for whom any treatments targeting a single diagnosis would leave significant difficulties unaddressed.

Study Details

Timeline

Phase 2CompletedFinished
201820192020202120222023202420252026
First PostedMay 8, 2017
Enrollment StartJul 18, 2017
Primary CompletionJul 31, 2020
TodayJul 2, 2026
Enrollment to primary: 3.0 yearsPosted 9.2 years ago

Interventions

The Modular Protocol for Mental Healthbehavioral

This intervention is based on evidence-based cognitive-behavioural approaches to psychological disorders and offers a flexible approach to treatment delivery that targets the maladaptive processes common to mood and anxiety disorders.

Treatment-as-usualbehavioral

This intervention will consist of psychological therapies delivered by high-intensity therapists or clinical psychologists.